Found 6 matching trials
A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor PHASE2 The current study is designed to evaluate the safety and efficacy, includin...
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Vertex Investigational Site
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24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate PHASE2 This study is designed to evaluate the safety and efficacy of VX-509, an or...
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Vertex Investigational Site
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A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid Arthritis PHASE2 This study is designed to evaluate the long-term safety and tolerability of...
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Vertex Investigational Site
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A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis PHASE2 This study is designed to evaluate safety and assess initial efficacy of VX...
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Multiple Locations
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Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects PHASE1 This study is designed to evaluate the effect of VX-509 on the pharmacokine...
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Vertex Investigational Site
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Single and Multiple Dose Escalation Study of VX-509 in Healthy Subjects PHASE1 Study to evaluate the safety and tolerability of single ascending doses and...
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Multiple Locations
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