Found 19 matching trials
Use of Thalidomide, Lenalidomide, Carfilzomib, Bortezomib and Vorinostat in the Initial Treatment of Newly Diagnosed Multiple Myeloma Patients PHASE3 The purpose of this study is to compare a standard chemotherapy regimen of ...
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112 sites UK wide
Treatments Being Tested
Induction (intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone (CRD) regimen Induction (intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone (CTD) regimen Induction (intensive pathway) - carfilzomib, cyclophosphamide, lenalidomide, & dexamethasone (CCRD) regimen Induction (non-intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone attenuated (CRDa) regimen Induction (non-intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone attenuated (CTDa) regimen Consolidation (intensive & non-intensive pathways) - bortezomib, cyclophosphamide, & dexamethasone (VCD) regimen Maintenance (intensive & non-intensive pathways) - lenalidomide maintenance Maintenance (intensive & non-intensive pathways - protocol v5.0 only) - lenalidomide plus vorinostat maintenance High dose melphalan therapy and autologous stem cell transplant (intensive pathway only) Learn More & Join Trial
Study of Isatuximab Combined With Bortezomib + Cyclophosphamide + Dexamethasone (VCD) and Bortezomib + Lenalidomide + Dexamethasone (VRD) in Newly Diagnosed Multiple Myeloma (MM) Non Eligible for Transplant or No Intent for Immediate Transplantation PHASE1 Primary Objectives:
* VCDI cohort:
* To determine the maximum tolerated...
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Investigational Site Number : 250002
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Collection of Additional Data Followed the Study IFM 2013-04 N/A Collection of retrospective additional data (survival, biological, disease ...
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Centre Hospitalier de la région d'Annecy
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Velcade (Bortezomib) Consolidation After Transplant PHASE3 The purpose of this study is to determine if bortezomib when added to conso...
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Multiple Locations
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Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique NA Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal co...
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Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma PHASE2 This study will assess whether the combination of daratumumab and carfilzom...
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Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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Tolerability and Efficacy of Modified VCD Regimens in Previously Untreated Multiple Myeloma. PHASE2 This phase 2 study will be conducted at 10 centers and enroll patients from...
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Clarithromycin in Multiple Myeloma Induction Therapy PHASE2 This study evaluates the potential synergic anti-myeloma activity of clarit...
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Department of Hematology, Aalborg University Hospital
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Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma PHASE2 This phase II trial investigates whether patients greater than or equal to ...
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University of Iowa Hospitals and Clinics
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Daratumumab for First Line Treatment of Transplant-ineligible Myeloma Patients Followed by Daratumumab Re-treatment at First Relapse PHASE2 Daratumumab for first line treatment of transplant-ineligible myeloma patie...
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Active Not Recruiting
Location
University of Cologne
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