Found 17 matching trials
4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer PHASE1 This trial studies the best dose and side effects of utomilumab (4-1BB agon...
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Stanford University, School of Medicine
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Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer PHASE2 The goal of this clinical research study is to learn if utomilumab, when gi...
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University of Texas MD Anderson Cancer Center
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A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab PHASE1 A study of PF-05082566, a 4-1BB agonist monoclonal antibody (mAb), in patie...
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Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer PHASE2 This phase II trial studies how well the combination of avelumab with lipos...
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Active Not Recruiting
Location
O'Neal Comprehensive Cancer Center
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A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley) PHASE1 This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacoki...
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UCSD Medical Center - Encinitas
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The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer PHASE2 This research study is studying a combination of drugs as a possible treatm...
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Active Not Recruiting
Location
University of Alabama at Birmingham
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A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors PHASE1 This study is a Phase 1b, open label, multi center, multi-dose trial design...
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UC San Diego Moores Cancer Center
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Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing PHASE3 This Master Protocol for Avelumab Continuation Sub-Studies is to provide co...
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Active Not Recruiting
Location
Highlands Oncology Group, PA
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Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies PHASE1 This phase I/II trial studies the side effects of avelumab when given in di...
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Active Not Recruiting
Location
M D Anderson Cancer Center
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A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B1641003/KEYNOTE-0036) PHASE1 This is a safety, pharmacokinetic and pharmacodynamic study designed to est...
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Research Administration Office
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