Found 12 matching trials
A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib PHASE1 This study is being done to look at how tucatinib could affect the way othe...
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Covance Clinical Research Unit
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A Study of Tucatinib (MK-7119) in Combination With Trastuzumab and Capecitabine in Participants With Previously Treated Locally Advanced Unresectable or Metastatic Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Breast Carcinoma (MK-7119-001) PHASE2 The goal of this study is to evaluate the efficacy and safety of tucatinib ...
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Active Not Recruiting
Location
Aichi Cancer Center Hospital ( Site 1013)
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Tucatinib Together With Pembrolizumab and Trastuzumab PHASE2 Women or men with HER2-positive, metastatic breast cancer, who have progres...
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Coffs Harbour Health Campus
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Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD PHASE2 A phase 2 non-randomized study to assess the safety and efficacy of the com...
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University of Alabama at Birmingham
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Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease PHASE2 The goal of this clinical trial is to evaluate the efficacy of tucatinib an...
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Institut Bergonié
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A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer PHASE1 DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour...
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Active Not Recruiting
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A Safety, Tolerability, and Pharmacokinetic Study of Tucatinib in Healthy Japanese and Caucasian Subjects PHASE1 This study is being done to compare the pharmacokinetics (PK) and safety/to...
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PAREXEL International, Early Phase Clinical Unit - Los Angeles
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The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer PHASE2 The purpose of this study is to test the safety and effectiveness of a sequ...
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Dana-Farber Cancer Institute
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Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002) PHASE1 The primary purpose of this study is to characterize the safety and tolerab...
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Active Not Recruiting
Location
Harbin Medical University Cancer Hospital
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Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients PHASE2 The aims of this study are to evaluate if an intensified adjuvant treatment...
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Fondazione Casa Sollievo della Sofferenza
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