Found 23 matching trials
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers PHASE2 This phase II trial compares the effect of usual treatment of docetaxel che...
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University of Alabama at Birmingham Cancer Center
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Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Trastuzumab Deruxtecan PHASE3 This study aims to evaluate whether the preventive and suppressive effects ...
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Second Affiliated Hospital of Zhejiang University School of Medicine
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PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer PHASE2 DEMETHER is a phase II trial exploring the maintenance of trastuzumab and p...
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Dana-Farber Cancer Institute
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Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer PHASE2 This study will evaluate the efficacy, safety, and pharmacokinetics of Tras...
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The University of Chicago
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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer PHASE2 The purpose of this study is to further advance the ability to practice per...
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University of Alabama at Birmingham
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A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) PHASE1 The purpose of this study is to evaluate the safety, tolerability, pharmaco...
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Mayo Clinic in Arizona
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Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC) PHASE2 This study was designed to evaluate the safety and efficacy of trastuzumab ...
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University of Colorado Denver - Anschutz Medical Campus
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Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors PHASE1 This is a study that will enroll patients with cancer who have tumors that ...
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University of Texas Health Science Center at San Antonio
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A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer PHASE3 This is open-label, multicenter, international study, assessing the efficac...
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Active Not Recruiting
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The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer PHASE2 The purpose of this study is to test the safety and effectiveness of a sequ...
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Dana-Farber Cancer Institute
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