Found 25 matching trials
SYD985 in Patients With HER2-expressing Recurrent, Advanced or Metastatic Endometrial Carcinoma PHASE2 The purpose of this study is to evaluate the safety and efficacy of SYD985 ...
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Smilow Cancer Hospital (Yale)
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Trastuzumab Deruxtecan to Treat HER2 + Newly Diagnosed Metastatic GI Cancers PHASE2 Purpose: This clinical trial is designed to evaluate the safety and effecti...
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Multiple Locations
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PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer PHASE2 DEMETHER is a phase II trial exploring the maintenance of trastuzumab and p...
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Active Not Recruiting
Location
Dana-Farber Cancer Institute
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DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03] PHASE3 This study is designed to compare the anti-tumor activity as well as the sa...
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Active Not Recruiting
Location
UCLA Hematology Oncology
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DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01) PHASE2 The main objective of this study is to test the safety and effectiveness of...
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City of Hope Medical Center
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A Study Of PF-05280014 Or Trastuzumab Plus Taxotere® And Carboplatin In HER2 Positive Breast Cancer In The Neoadjuvant Setting (REFLECTIONS B327-04) PHASE3 The current study will compare PK, efficacy, safety, and immunogenicity of ...
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Compassionate Cancer Care Medical Group, Inc.
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A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) PHASE1 The purpose of this study is to evaluate the safety, tolerability, pharmaco...
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Mayo Clinic in Arizona
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JSKN003 Versus Trastuzumab Emtansine (T-DM1) for HER2-Positive, Advanced Breast Cancer PHASE3 This study is designed to compare the safety and efficacy of JSKN003 versus...
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Fudan University Shanghai Cancer Center
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Phase 1 Study of Trastuzumab Administered as a Single Intravenous Infusion PHASE1 The primary objective of this study was to demonstrate pharmacokinetic simi...
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Multiple Locations
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Roll-Over Study of Alpelisib (BYL719) for Continued Access and Long-Term Safety. PHASE2 The purpose of this study is to provide post-trial access to alpelisib and ...
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Multiple Locations
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