Found 307 matching trials
Pembrolizumab and Trametinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer and KRAS Gene Mutations
PHASE1This phase Ib trial studies the side effects of pembrolizumab and trametini...
Location
University of California Davis Comprehensive Cancer Center
Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma
PHASE2This phase II trial studies how well dabrafenib, trametinib, and spartalizu...
Location
M D Anderson Cancer Center
Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study
NAThis study is looking at outcomes in people with advanced cancers who have ...
Location
Peter MacCallum Cancer Centre
Neoadjuvant Therapy With Conservative Surgery vs. Up-front Conservative Surgery for BRAF V600E-Mutated Ameloblastoma
PHASE2Ameloblastoma is the most common benign odontogenic tumor, characterized by...
Location
Multiple Locations
Dabrafenib + Trametinib + PDR001 In Colorectal Cancer
PHASE2This research study is studying a combination of drugs as a possible treatm...
Location
Massachusetts General Hosital Cancer Center
Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation
PHASE2This is a single arm phase II trial focused on how dabrafenib and trametini...
Status
Active Not Recruiting
Location
M D Anderson Cancer Center
TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma
PHASE2This phase 2 trial will investigate the efficacy and safety of trametinib a...
Location
Universitair Ziekenhuis Brussel
Safety, Pharmacokinetics (PK) of AKT and MEK Combination
PHASE1This study is a Phase 1 dose-escalation open-label study to determine the r...
Location
GSK Investigational Site
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
NAThis pilot clinical trial studies the feasibility of choosing treatment bas...
Location
Fred Hutch/University of Washington Cancer Consortium
A Clinical Trial of Patients With Melanoma
PHASE1This study is being done to find out if the combination of dabrafenib, tram...
Location
University of Texas Southwestern Medical Center