Found 8 matching trials
Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease. PHASE3 Phase 3, international, multicenter, open-label 12 month safety study....
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Barrow Neurology Clinics, St. Joseph's Hospital and Medical Center, Dignity Health
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Safety and Efficacy Study of SYN115 in Parkinson's Patients Using Levodopa to Treat End of Dose Wearing Off PHASE2 The purpose of this research study is to test the effect of SYN115 compared...
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Multiple Locations
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Study to Evaluate the Absorption, Distribution, Break Down and Elimination and the Safety of 14C-Labeled Tozadenant PHASE1 The purpose of the study is to investigate how tozadenant is absorbed, dist...
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Pharmaceutical Research Associates Group B.V.
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Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Tozadenant PHASE1 This is a two-part, open label, single-dose study that will evaluate the PK...
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University of Miami
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Study to Evaluate SYN115 in Parkinson's Disease PHASE2 This is an exploratory study to evaluate if SYN115 has an effect on Parkins...
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Washington University St. Louis
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An fMRI Study of SYN115 in Cocaine Dependent Subjects EARLY_PHASE1 The dopamine system is critical in modulation of reward and has been implic...
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University of Texas Health Science Center at Houston
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A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users PHASE1 This will be a single-dose, randomized, double-blind, active- and placebo-c...
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INC Research Toronto, Inc.
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Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients PHASE3 Phase 3, international, multicenter, randomized, double-blind, placebo-cont...
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Multiple Locations
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