Found 11 matching trials
Tosedostat With Capecitabine in Patients With Metastatic Pancreatic Adenocarcinoma PHASE1 There are two parts to this study: the goal of the first part of the study ...
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Washington University School of Medicine
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Clinical Trial of the Safety and Effectiveness of CHR-2797 With Erlotinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer PHASE1 This is an open-label, multicenter, multiple-dose, Phase I-II study of CHR-...
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Tower Cancer Research Foundation
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Study of Clinical Efficacy and Safety of Tosedostat in MDS PHASE2 Study WCMC IST-CTI-MDS evaluates the safety and tolerability of tosedostat ...
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Weill Cornell Medical College
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Tosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome PHASE2 This study examines a new oral chemotherapy drug called tosedostat, in comb...
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Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
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A Study of the Safety and Tolerability of the Addition of CHR-2797 to Paclitaxel in Patients With Advanced or Refractory Tumours PHASE1 The treatment of cancer often involves the use of more than one drug at the...
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Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome PHASE1 This phase I/II trial studies the side effects and best dose of cytarabine ...
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M D Anderson Cancer Center
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Safety and Anti-Disease Activity of Oral Tosedostat (CHR-2797) in Elderly Subjects With Refractory or Relapsed AML PHASE2 The purpose of this study is to evaluate the efficacy and safety of tosedos...
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UCLA School of Medicine
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Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemia PHASE2 The purpose of this study is to evaluate the long-term efficacy and safety ...
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UCLA Division of Hematology/Oncology
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Safety Study to Evaluate CHR-2797 in Patients With Advanced Tumours PHASE1 The primary objective of this study was to determine the safety, tolerabili...
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Multiple Locations
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Crossover Trial of the Effect of a High-Fat Meal on the PK of Oral CHR 2797 in Healthy Male Subjects PHASE1 The objectives of this study are to evaluate the safety and tolerability; a...
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Covance Clinical Research Unit Inc.
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