Found 16 matching trials
Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
PHASE2The purpose of this research study is to test an experimental treatment met...
Location
Nicklaus Children's Hospital
Reducing Hypoxia in Patients With Coronavirus Disease (COVID-19) Using Topotecan With Standard of Care
PHASE1The primary objective of the phase 1 trial is to identify a dose of topotec...
Location
Christian Medical College
Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
PHASE11. To find the optimal dose of topotecan that can safely be given directly ...
Location
Texas Children's Hospital
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
PHASE1This is a Phase I trial with new experimental drugs such as simvastatin in ...
Location
Children's Healthcare of Atlanta/Emory University
Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery
PHASE2This is a prospective phase II study to assess the efficacy and toxicity of...
Location
Houston Methodist Hospital
Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment
PHASE2Drugs used in chemotherapy use different ways to stop tumor cells from divi...
Location
Children's Oncology Group
Arsenic Trioxide With MAPK Inhibitors and Chemotherapy for Stage 4/M Neuroblastoma
PHASE2This prospective, single-arm, multi-center clinical trial aims to explore a...
Location
Sun Yat-sen Memorial Hospital
SHR - A1811 Versus Chemotherapy for Platinum-resistant Recurrent Epithelial Ovarian Cancer
PHASE3This study is a randomized, open-label, active-controlled, multicenter phas...
High-dose Topotecan for Retinoblastoma With Recurrent or Refractory Vitreous Seed
EARLY_PHASE1Retinoblastoma is the most common intraocular malignancy in infancy and chi...
Location
Fudan Eye & ENT Hospital
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
EARLY_PHASE1Pilot study to determine feasibility of adding intrathecal chemotherapy and...
Location
Alberta Children's Hospital