Found 12 matching trials
Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function PHASE1 The purpose of this parallel group, Phase 1, open-label, 2-arm, single dose...
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Clinical Pharmacology of Miami Site Number : 8400002
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Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS) PHASE3 Primary Objective:
To determine the efficacy of SAR442168 compared to plac...
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UC San Diego ACTRI Site Number : 8400101
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Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Renal Impairment Compared to Healthy Participants. PHASE1 The purpose of this parallel group, Phase 1, open-label, 2-arm study is to ...
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Clinical Pharmacology of Miami Site Number : 8400002
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Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 1) PHASE3 Primary Objective:
To assess efficacy of daily SAR442168 compared to a dai...
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University of Alabama MS Center-Site Number:8400013
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A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis. PHASE3 This is a Phase 3 extension, global, multicenter study to assess the long-t...
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Active Not Recruiting
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The University of Alabama at Birmingham- Site Number : 8400013
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Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 2) PHASE3 Primary Objective:
To assess efficacy of daily SAR442168 compared to a dai...
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North Central Neurology Associates, PC-Site Number:8400009
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Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis PHASE3 This was a multicenter, randomized, double-blind, placebo-controlled, Phase...
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Georgetown University-Site Number:8400008
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Study of the Tolerability and Pharmacokinetics of Oral Doses of SAR442168 With a Food Effect Investigation in Healthy Adult Participants PHASE1 This is a randomized, placebo-controlled, four-part, Phase I, first in huma...
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New Orleans Clinical Research Site Number : 8400001
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Long Term Safety and Efficacy Study of Tolebrutinib (SAR442168) in Participants With Relapsing Multiple Sclerosis PHASE2 Primary Objective:
To determine the long-term safety and tolerability of S...
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North Central Neurology Associates, PC Site Number : 8400005
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Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES) PHASE3 Primary Objective:
To determine the efficacy of SAR442168 compared to plac...
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University of Alabama MS Center-Site Number:8400013
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