Found 12 matching trials
Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations PHASE3 This is an open-label, randomized, controlled, multicenter, phase III clini...
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Anhui Provincial Hospital
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Safety of TT-00420 (Tinengotinib) Monotherapy in Patients With Advanced Solid Tumors and Triple Negative Breast Cancer PHASE1 This is a first-in-human, phase I clinical research study with TT-00420, an...
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MD Anderson Cancer Center
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A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC. PHASE2 An Open-label, Multicenter, Phase II Clinical Study of AK104/AK112 in Combi...
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Union Hospital Tongji Medical College Huazhong University of Science And Technology
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Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors PHASE1 This is a Phase Ib/II, multicenter, open-label study to evaluate the safety...
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Efficacy and Safety of Tinengotinib Tablets Combined With Fulvestrant Injection in Patients With HR Positive and HER-2 Negative Recurrent or Metastatic Breast Cancer Who Have Failed Prior Treatment PHASE2 The goal of this clinical trial is to learn if tinengotinib combined with f...
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Guangdong Provincial People's Hospital
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Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR Inhibitor PHASE2 A phase II, open-label, multicenter study to evaluate the efficacy and safe...
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Active Not Recruiting
Location
Anhui Provincial Hospital
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To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors PHASE1 This is a Phase Ib/II, multicenter, open-label study to evaluate the safety...
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The First Affiliated Hospital of Wannan Medical College
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Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma PHASE2 This study is an open-label, multicenter study to evaluate the efficacy and...
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Providence Cancer Center
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Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers PHASE1 This study is an open-label, 3-way crossover randomized study in adult heal...
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Rollover Study to Provide Continued Access to TT-00420 (Tinengotinib) for Subjects With Advanced Solid Tumors N/A This study is an open-label, multicenter study for Continued Characterizati...
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University of Chicago Medical Center
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