Found 21 matching trials
5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
PHASE1This phase I trial is studying the side effects and best dose of 5-Fluoro-2...
Cytochlor, Tetrahydrouridine, and External-Beam Radiation Therapy in Treating Patients With Cancer That Has Spread to the Brain
PHASE1RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. D...
Location
University of Miami
FdCyd and THU for Advanced Solid Tumors
PHASE1Background:
\- FdCyd (also called 5-fluoro-2'-deoxycytidine) and THU (also...
Effect of Food on the Pharmacokinetics of Decitabine/Tetrahydrouridine Combination Capsules in Healthy Adult Subjects
PHASE1This study is to investigate the effect of a high fat meal on the pharmacok...
Location
Worldwide Clinical Trial
Randomized, Single-dose, Crossover Study of 4 Decitabine and Tetrahydrouridine (EPI01) Formulations in Healthy Subjects
PHASE1To study the pharmacokinetic profiles of decitabine and tetrahydrouridine (...
Location
Worldwide Clinical Trial
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
PHASE1Background:
Most patients who have surgery for cancer that has metastasize...
Location
Multiple Locations
A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS)
PHASE1The goal of this clinical trial is to learn about the safety and effectiven...
Location
Montefiore Einstein Medical Center
A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
PHASE1A randomized control trial in 20 subjects with sickle cell disease comparin...
Location
University of Illinois at Chicago College of Medicine
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer
PHASE1This phase I trial studies the side effects and best dose of 5-fluoro-2-deo...
Location
City of Hope National Medical Center
Imaging Study for FdCyd and THU Cancer Treatment
EARLY_PHASE1Background:
\- The drugs FdCyd (also called 5-fluoro-2'-deoxycytidine) and...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike