Found 24 matching trials
Treatment of Graves' Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in an Open-Label Clinical Extension Study PHASE3 The overall objective is to evaluate the safety and efficacy of teprotumuma...
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The Safety and Efficacy of Sequential Hormone Therapy and IBI311 Therapy in Patients With Active Moderate to Severe TAO in the Initial Treatment. PHASE4 Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune dis...
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Shanghai Changzheng Hospital
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A Trial to Investigate Teprotumumab (High-concentration Formulation) Subcutaneous Administration in Healthy Adult Non-Japanese and Japanese Participants PHASE1 The primary objective of this trial are to assess the pharmacokinetics (PK)...
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PPD Development, LP
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A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease PHASE2 LASN01 is a novel, fully human antibody directed against the human IL-11 re...
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A Clinical Study to Evaluate the Efficacy and Safety of IBI311 in Subjects With Inactive Thyroid Eye Disease PHASE3 A multicenter clinical study to evaluate the efficacy and safety of IBI311 ...
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The First Affiliated Hospital of Medical University
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Teprotumumab N01 Versus Methylprednisolone After Urgent Orbital Decompression for Dysthyroid Optic Neuropathy PHASE2 This study aims to evaluate the efficacy and safety of sequential Teprotumu...
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Zhongshan Ophthalmic Center, Sun Yat-sen University
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A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) PHASE1 The overall objective is to investigate the safety, tolerability and effect...
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UCLA Division of Rheumatology
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Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study PHASE3 The overall objective is to investigate the efficacy, tolerability, and saf...
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Expanded Access Protocol of Teprotumumab (HZN-001) for Patients With Active Thyroid Eye Disease N/A This is an expanded access protocol intended to provide access to teprotumu...
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Approved For Marketing
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A Study of TEPEZZA Subcutaneous Administration in Healthy Adults PHASE1 The primary objective of this study is to assess the pharmacokinetics (PK) ...
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