Found 10 matching trials
Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer PHASE1 This partially randomized phase Ib/II trial studies the side effects and be...
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University of Alabama, Birmingham
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A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy PHASE3 This international, multicenter, randomized, double-blinded, placebo-contro...
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PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib PHASE1 Part A: This is a phase Ib trial combining the CDK4/6 inhibitor palbociclib...
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The Royal Marsden NHS Foundation Trust
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) PHASE2 This phase II MATCH screening and multi-sub-trial studies how well treatmen...
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Active Not Recruiting
Location
University of Alabama at Birmingham Cancer Center
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Phase Ib Dose-escalation Trial of Taselisib (GDC-0032) in Combination With Anti-HER2 Therapies in Participants With Advanced HER2+ Breast Cancer PHASE1 This research study is a way of gaining new knowledge about the combination...
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Massachusetts General Hospital
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A Study of Neoadjuvant Letrozole + Taselisib Versus Letrozole + Placebo in Post-Menopausal Women With Breast Cancer (LORELEI) PHASE2 This is a two-arm, randomized, double-blind, multicenter, pre-operative stu...
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Breastlink Med Group Inc
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Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer N/A This screening and multi-sub-study randomized phase II/III trial will estab...
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University of Alabama at Birmingham Cancer Center
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Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I) PHASE2 This phase II MATCH treatment trial identifies the effects of GDC-0032 (tas...
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Active Not Recruiting
Location
ECOG-ACRIN Cancer Research Group
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Trial of Taselisib in Overgrowth PHASE1 Segmental overgrowth disorders are rare conditions characterised by abnorma...
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Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches PHASE2 This phase II trial studies how well taselisib (GDC-0032) works in treating...
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University of Alabama at Birmingham Cancer Center
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