Found 14 matching trials
Lp(a) Lowering Study of Pelacarsen (TQJ230) in Patients in the US With Elevated Lp(a) and Recent ACS (STEMI/NSTEMI) - Lp(a)FRONTIERS PEARL PHASE3 CTQJ230A1US13 is a randomized, double-blind, placebo-controlled, multicente...
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Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD PHASE3 This is a pivotal phase 3 study designed to support an indication for the r...
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SEC Clinical Research LLC
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Pelacarsen Roll-over Extension Program PHASE3 This non-randomized, rollover extension study will provide post-trial acces...
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Parkway Medical Center
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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany PHASE3 Phase III study to test the hypothesis that treatment with pelacarsen (TQJ2...
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Novartis Investigative Site
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Managed Access Programs for TQJ230, Pelacarsen N/A The purpose of this registration is to list Managed Access Programs (MAPs) ...
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Multiple Locations
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A Study to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pelacarsen (ISIS 681257) in Healthy Japanese Participants PHASE1 The purpose of the study is to assess the safety, tolerability, and pharmac...
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Parexel International
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Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease PHASE2 This is a multicenter, randomized, double-blind, placebo-controlled, dose-r...
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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) PHASE3 This open-label extension study will provide post-trial access to pelacarse...
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SEC Clinical Research LLC
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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis PHASE2 The purpose of this study is to evaluate the efficacy, safety and tolerabil...
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Heart Center Research Llc
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Study to Assess the Pharmacokinetics of Pelacarsen (TQJ230) in Participants With Mild Hepatic Impairment Compared to Matched Healthy Participants PHASE1 This was a Phase I, open-label, single-dose, parallel-group study in partic...
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Novartis Investigative Site
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