Found 22 matching trials
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors PHASE1 Approximately 90% of children with malignant brain tumors that have recurre...
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St. Jude Children's Research Hospital
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Compassionate Use Program BRAF Mutation-positive Patients in the Adjuvant Treatment of Melanoma After Surgical Resection N/A The purpose of this Treatment Plan is to allow access to trametinib and dab...
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No Longer Available
Location
Multiple Locations
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Compassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic Melanoma N/A The purpose of this Cohort Treatment Plan is to allow access to trametinib ...
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No Longer Available
Location
Multiple Locations
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Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers PHASE2 This was a Phase II, open-label, non-randomized, multi-center study of oral...
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Novartis Investigative Site
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Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors PHASE1 Phase Ib dose escalation in advanced solid tumors to identify dose for Phas...
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Highlands Oncology Group
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Pediatric Long-Term Follow-up and Rollover Study PHASE4 A roll-over study to assess long-term effect in pediatric patients treated ...
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Active Not Recruiting
Location
Phoenix Children s Hospital
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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia PHASE1 This clinical trial will test the safety and efficacy of combining trametin...
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Phoenix Children's Hospital
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Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors PHASE2 The purpose of this study was to investigate the activity of dabrafenib in ...
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Children's Hospital of Orange County
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24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs PHASE2 The purpose of this study is to assess the effectiveness and safety of Tram...
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Active Not Recruiting
Location
Children's Hospital of Philadelphia
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Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma PHASE2 This phase II trial investigates how well adding hydroxychloroquine to the ...
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Anchorage Associates in Radiation Medicine
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