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Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients PHASE2 Several trials showed that total neoadjuvant treatment (TNT) in stage II/II...
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Clinical oncology and nuclear medicine Department, Faculty of medicine, Ain Shams University
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Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision NA The purpose of this research protocol is the evaluation of the improvement ...
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University Hospital of Larissa
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Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation PHASE3 Preoperative radiation and chemotherapy is the standard treatment for local...
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Cancer center of Sun Yat-sen University
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Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer PHASE2 Colorectal cancer of Mismatch Repair-proficient (pMMR)/ Microsatellite Stab...
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Second Affiliated Hospital School of Medicine Zhejiang University
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Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma PHASE3 Short-course radiotherapy combined with immunotherapy may bring revolutiona...
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
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Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer NA The goal of this clinical trial is to test the safety and efficacy of local...
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Peking University Cancer Hospital & Institute
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Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II) PHASE2 Most rectal cancers are microsatellite stable (MSS) or mismatch repair-prof...
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The Sixth Affiliated Hospital of Sun Yat-sen University
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Multicenter Study on Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients NA TME (Total mesorectum excision) is the golden standard of radical resection...
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The Third Affiliated Hospital of Sun Yat-sen University
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Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients NA Whether to perform radical TME or salvage chemoradiotherapy after local res...
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Gastrointestinal Hospital, Sun Yat-sen University
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A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis PHASE2 Although patients with locally advanced rectal cancer and resectable liver/...
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Fudan University Shanghai Cancer Center
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