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Trial Search

Current Search Criteria:

Intervention: TMC435

Found 111 matching trials

A Study to Examine Patient Characteristics, Health Care Management and Health Outcomes of Hepatitis C Virus (HCV) Patients Treated With Simeprevir

N/A

The purpose of this study is to evaluate the effectiveness of a simeprevir-...

Status

Completed

Location

Multiple Locations

Start Date

2014-02

Trial ID

NCT02103699

Treatments Being Tested

No intervention

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

PHASE1

The purpose of this study is to evaluate the pharmacokinetics (PK) of AL-33...

Status

Withdrawn

Location

Multiple Locations

Start Date

2017-09-11

Trial ID

NCT03277755

Treatments Being Tested

AL-335 800 mg ODV 25 mg SMV 75 mg

TMC435-TiDP16-C125 - Study in Healthy Volunteers to Evaluate the Potential of TMC435 to Increase the Sensitivity of the Skin Towards Exposure to Sun Light

PHASE1

The purpose of the study is to evaluate the potential effect of TMC435 on t...

Status

Completed

Location

Multiple Locations

Start Date

2010-07

Trial ID

NCT01124799

Treatments Being Tested

TMC435 Placebo Ciprofloxacin

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Chronic Hepatitis C Virus Infection Without Cirrhosis

PHASE3

The purpose of the study is to evaluate the efficacy and safety of a treatm...

Status

Completed

Location

Multiple Locations

Start Date

2014-04

Trial ID

NCT02114177

Treatments Being Tested

Simeprevir Simeprevir Sofosbuvir Sofosbuvir

TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients

PHASE1

The purpose of this study is to assess the safety and tolerability of TMC64...

Status

Completed

Location

Multiple Locations

Start Date

2010-04

Trial ID

NCT01202825

Treatments Being Tested

TMC647055 Placebo TMC647055 TMC647055 Placebo TMC435 Placebo TMC647055 Placebo TMC647055

TMC435-TiDP16-C123 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents Efavirenz and Raltegravir

PHASE1

The purpose of this study is to investigate the effect of steady-state conc...

Status

Completed

Location

Multiple Locations

Start Date

2010-10

Trial ID

NCT01241773

Treatments Being Tested

raltegravir TMC435 + raltegravir TMC435 TMC435 + efavirenz TMC435 efavirenz

An Observational Study Examining the Use of Triple Combination Therapy With Boceprevir, Peginterferon Alfa-2a and Ribavirin in the Re-Treatment of Chronic Hepatitis C Patients

N/A

This prospective, national, multicenter, non-interventional study examined ...

Status

Terminated

Location

Multiple Locations

Start Date

2014-05

Trial ID

NCT02118597

Treatments Being Tested

Boceprevir Simeprevir Pegylated Interferon (Peginterferon) Alfa-2a Ribavirin

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Subjects With Chronic Genotype 4 Hepatitis C Virus Infection

PHASE3

The purpose of this study is to show superiority of simeprevir (SMV) in com...

Status

Completed

Location

Multiple Locations

Start Date

2015-01

Trial ID

NCT02250807

Treatments Being Tested

Simeprevir Sofosbuvir

Sofosbuvir With Ribavirin or Simeprevir With HCV GT4 Egyptian Patients

PHASE2

A total of 201 participants with chronic HCV GT4 infection were allocated i...

Status

Completed

Location

Multiple Locations

Start Date

2015-04

Trial ID

NCT04385407

Treatments Being Tested

Sofosbuvir + Simeprevir + Ribavirin

A Study of the Safety and Effectiveness of Simeprevir and Sofosbuvir for Patients With HIV and Hepatitis C

PHASE4

This is a study of the safety and effectiveness of the hepatitis C medicati...

Status

Withdrawn

Location

San Francisco General Hospital, University of California, San Francisco

Start Date

2014-08

Trial ID

NCT02206932

Treatments Being Tested

Sofosbuvir + Simeprevir

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