Found 845 matching trials
Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer PHASE2 This phase II trial studies the effect of bintrafusp alfa with pemetrexed a...
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M D Anderson Cancer Center
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Study of Osimertinib+Bevacizumab+Chemotherapy for EGFR+ Advanced Non-Small Cell Lung Cancer With Concurrent Mutations PHASE2 This is a single-center, open-label, phase I clinical trial aimed to evalua...
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Tianjin Medical University Cancer Institute and Hospital
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A Platform Trial for Personalized and Adaptive Therapies in Hepatocellular Carcinoma PHASE2 This is a phase II, multi-arm, Bayesian adaptive platform trial designed to...
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Zhongshan Hospital, Fudan University
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Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC PHASE2 According to literature reports, about 16.3%-19% of newly diagnosed NSCLC p...
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Chongqing University Cancer Hospital
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A Comparison of Vorolanib Tablets Combined With Everolimus Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma Who Have Progressed After Treatment With Immunotherapy Monotherapy or in Combination With TKI PHASE3 This study is a multicenter, open-label, randomized controlled trial that e...
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Peking University Cancer Hospital
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A Study of FWD1509 in Adults With Non-Small Cell Lung Cancer PHASE1 The purpose of this study is to characterize the safety and tolerability of...
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Gabrail Cancer Center
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Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations PHASE1 BDTX-1535-101 is an open-label, Phase 1 dose escalation and Phase 2 multipl...
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Active Not Recruiting
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University of Alabama
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Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System PHASE3 Tyrosine kinase inhibitors (TKI) have revolutionized the management and pro...
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Active Not Recruiting
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Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib PHASE1 The purpose of this randomized study is to determine the safety and efficac...
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Valkyrie Clinical Trials
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Conversion Therapy of Sintilimab in Combination With Apatinib and Chemotherapy in Stage IV Gastric Cancer PHASE2 This is a single-arm, phase II study aiming to evaluate the feasibility and...
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Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital
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