Found 6 matching trials
TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma PHASE1 This is an open-label, phase 1 trial evaluating the safety of oncolytic ade...
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Location
National Center for Cancer Immune Therapy Herlev Hospital, Copenhagen University
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Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer. PHASE1 This is an open-label, phase 1/1b, dose-escalation, multicenter and multina...
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Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer PHASE1 This is an open label, Phase 1, dose escalation trial evaluating the safety...
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Location
Hoag Memorial Hospital Presbyterian
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TNFalpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 During TIL Treatment of Advanced Melanoma PHASE1 This is an open-label, phase 1, first-in-human (FIH), dose-escalation, mult...
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National Center for Cancer Immune Therapy Herlev Hospital, Copenhagen University
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TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 Monotherapy PHASE1 This is an open-label, phase 1, dose-escalation, multicenter trial evaluati...
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Helsinki University Hospital
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Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1 PHASE1 This is a phase 1, dose-escalation trial evaluating the safety of oncolytic...
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Location
Memorial Sloan Kettering Cancer Center
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