Found 24 matching trials
A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure PHASE2 The aim of this study was to determine whether long-term (≥ 6 months at the...
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University of Alabama at Birmingham
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Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients PHASE3 The safety and efficacy at 100 mg once daily for oral dose of sitaxentan so...
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Pfizer Investigational Site
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Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3) EARLY_PHASE1 Endothelin-1 (ET-1) has been linked to a number of conditions including pul...
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Clinical Research Centre, Western General Hospital
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A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension PHASE3 This is a multi-center, open-label study of sitaxsentan sodium 100 mg taken...
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Pfizer Investigational Site
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A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses PHASE1 Sitaxsentan has a low drug-drug interaction potential and it did not have a...
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Pfizer Investigational Site
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Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma PHASE2 Introduction. Despite adequate steroid therapy, a subpopulation of approxim...
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Clinical Investigation center 07, Hopital Bichat
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Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery PHASE2 This is a multi-center, randomized study of sitaxsentan administered intrav...
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University of Pennsylvania,
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Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan PHASE1 This study will assess how rifampin will affect the blood levels of sitaxse...
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Multiple Locations
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Drug Interaction Between Ritonavir And Sitaxsentan PHASE1 The study is to assess if sitaxsentan and ritonavir will affect the blood l...
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Multiple Locations
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Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil PHASE3 As monotherapy for pulmonary arterial hypertension (PAH) begins to fail add...
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Pfizer Investigational Site
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