Found 33 matching trials
Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) PHASE4 The purpose of this study was to understand whether participants could moun...
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Novartis Investigative Site
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Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND) PHASE3 Evaluate the safety and efficacy of Siponimod (BAF312) versus placebo in a ...
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Novartis Investigative Site
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COVID-19 Vaccine Response in Treated MS Patients N/A The primary goal of this study is to assess the impact of the two major dis...
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Brigham MS Center
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Post-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent N/A This study will utilize a prospective, observational, exposure cohort desig...
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Novartis Investigative Site
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A Single-dose, Open-label, Parallel-group Study to Assess the Pharmacokinetics of BAF312 in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function PHASE1 to quantify the effect of different degrees of renal impairment on the phar...
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Novartis Investigative Site
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Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis PHASE2 To assess the efficacy of Mayzent on microglia pathology in patients with a...
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University at Buffalo, Buffalo General Hospital
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Characterization of Early Patients Initiating Ofatumumab for Treatment of Multiple Sclerosis. N/A This was a retrospective cohort study utilizing secondary data from IQVIA's...
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Novartis Investigative Site
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Single Dose Study to Assess the Safety, Tolerability, Concentration in Body and Effect of BAF312 PHASE1 The purpose of this study is to assess the safety, tolerability, and effect...
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Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS PHASE4 The DELIVER-MS study seeks to answer the question: Does early treatment wit...
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Active Not Recruiting
Location
University of Colorado-Anschutz Medical Campus
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Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS Patients PHASE3 To assess safety and tolerability of patients converting from approved Rela...
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Novartis Investigative Site
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