🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

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🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: Single-cell sequencing and spatial transcriptome sequencing

Found 12 matching trials

Clinical Outcomes and Immunotherapy in Lung Cancer With Pulmonary Fibrosis

N/A

This retrospective observational study evaluates immune checkpoint inhibito...

Status

Active Not Recruiting

Location

The First Affiliated Hospital of Nanjing Medical University

Start Date

2025-11-01

Trial ID

NCT07396467

Treatments Being Tested

there is no intervention

"Immunoregulation in Atherosclerosis: A Single-Cell RNA Sequencing Study"

N/A

Atherosclerosis is the leading cause of acute cardiovascular events, such a...

Status

Not Yet Recruiting

Location

Hospital Israelita Albert Einstein

Start Date

2025-06-25

Trial ID

NCT06860295

Treatments Being Tested

Single Cell RNA Sequencing

Biological Analysis of MABs in NHL in a Translational Prospective Observational Study Within Italian Clinical Practice

N/A

This a prospective, multicenter, observational pharmacological translationa...

Status

Not Yet Recruiting

Location

Ematologia - Fondazione del Piemonte per l'Oncologia - IRCCS

Start Date

2026-10

Trial ID

NCT07767799

Treatments Being Tested

WP1 - Task 1 - Liquid analyses WP1 - Task 2 - Immunological analyses WP1 - Task 3 - Tumor tissue analyses WP1 - Task 4 - Imaging analyses WP1 - Task 5 - Microbiome and metabolomics analyses WP2 - Task 1 - Liquid analyses WP2 - Task 2 -Immunological analyses WP2 - Task 3 - Tumor tissue analyses WP2 - Task 4 - Imaging analyses WP2 - Task 5 - Microbiome and metabolomics analyses WP3 - Task 1 - Liquid analyses WP3 - Task 2 - Immunological analyses WP3 - Task 3 - Tumor tissue analyses WP3 - Task 4 - Imaging analyses WP3 - Task 5 - Microbiome and metabolomics analyses

Research on the Potential Mechanisms Underlying the Efficacy Differences in Specific Neoadjuvant Treatment Regimens for Different Subtypes of Breast Cancer

This study is a single-center, open-label, prospective, clinical cohort stu...

Status

Recruiting

Location

Xijing hospital

Start Date

2024-04-01

Trial ID

NCT07012720

Treatments Being Tested

Single-cell sequencing and spatial transcriptome

Gene Expression Changes of Brain Tissue in Human Temporal Lobe Epilepsy With Hippocampal Sclerosis

N/A

Epilepsy is a common neurological disease, manifested in the sudden abnorma...

Status

Active Not Recruiting

Location

2ndAffiliated Hospital, School of Medicine, Zhejiang University, China

Start Date

2021-04-19

Trial ID

NCT04917939

Treatments Being Tested

RNA sequencing

Multi-omics Analysis of Renal Cell Carcinoma Mechanisms; Drug Sensitivity Testing in Patient-Derived Cell-based Microtumors

N/A

This is a research study aiming to better understand a type of kidney cance...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2026-01-25

Trial ID

NCT07351266

Treatments Being Tested

Multi-region Tumor Sampling and Integrated Multi-omics Analysis and Microtumor PTC Drug Sensitivity Assay

Multi-Omics Insights Into Androgenetic Alopecia

N/A

This study utilizes a multi-omics approach to systematically characterize t...

Status

Recruiting

Location

The First Affiliated Hospiatl of Henan Medical University

Start Date

2026-03-08

Trial ID

NCT07603544

Treatments Being Tested

Collection of ~2 × 12 mm scalp tissue Single-cell sequencing and spatial transcriptome sequencing

A Biomarker Exploratory Study of Dual Blockade of PD1/PDL1 and CTLA4 and Anti-angiogenic Therapy

N/A

This study is a single-center prospective exploratory research, aiming to i...

Status

Recruiting

Location

Jian Li

Start Date

2024-01-10

Trial ID

NCT06549907

Treatments Being Tested

Multi-omics testing MRI

Tumor Microenvironment Changes After Neoadjuvant Chemo-Immunotherapy in Esophageal Squamous Cell Carcinoma

N/A

This prospective observational study aims to characterize dynamic changes i...

Status

Not Yet Recruiting

Location

Multiple Locations

Start Date

2026-06-01

Trial ID

NCT07482774

Treatments Being Tested

Biological: Tumor Tissue and Blood Sample Collection

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

N/A

The purpose of this study is to cast light on the highly complex etiology a...

Status

Recruiting

Location

PET-centre, University of Turku

Start Date

2023-01-11

Trial ID

NCT05278520

Treatments Being Tested

Total hip arthroplasty

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