Found 51 matching trials
To Observe the CD7-targeted CAR-T Therapy in the Treatment of MRD Positive T-ALL/LBL Post Allo-HSCT PHASE1 To observe the efficacy and safety of CD7-targeted chimeric antigen recepto...
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Peking University People's Hospital
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Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma PHASE1 This study is designed to evaluate the efficacy and safety of sintilimab-be...
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Multiple Locations
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Bispecific Antibody-Based Salvage Therapy Followed by CAR-T ± ASCT in R/R Aggressive B-Cell Lymphoma PHASE2 This study consists of two sequential treatment phases. In the first phase,...
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Institute of Hematology & Blood Diseases Hospital
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CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa) PHASE1 Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, ...
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Multiple Locations
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A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1 Background:
GM1 gangliosidosis is a disorder that destroys nerve cells. It...
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National Institutes of Health Clinical Center
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Phase I Study of TX103 CAR-T Cells in Participants With Advanced Solid Tumors PHASE1 This is a single-arm, open-label, Phase I study to evaluate the safety, tol...
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Beijing Cancer Hospital
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TheraSphere With Durvalumab and Tremelimumab for HCC PHASE2 The objective of the ROWAN clinical study is to assess the efficacy of loca...
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Active Not Recruiting
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University of California San Diego
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ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL NA This open-label, non-randomized, phase II exploratory study aims to evaluat...
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Blood diseases hospital
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A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. EARLY_PHASE1 This clinical trial is studying a drug called SGT-53 along with radiation a...
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Children's National Hospital
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IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL PHASE1 This study is being done to determine the safety, efficacy and tolerability...
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University of Texas Southwestern Medical Center
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