Found 27 matching trials
Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity PHASE3 This pivotal, phase 3 study is designed to confirm the efficacy and safety ...
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Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity PHASE3 To demonstrate statistically significant and clinically meaningful effects ...
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Honor Health Research Institute
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Study of Setmelanotide Effects on QTc (Corrected QT) Interval in Healthy Participants PHASE4 This was a double-blind, randomized, placebo- and positive-controlled, para...
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Parexel Early Phase Clinical Unit (Los Angeles)
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A Trial of Setmelanotide in Acquired Hypothalamic Obesity PHASE3 The goal of this trial is to learn how well Setmelanotide works to improve ...
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Active Not Recruiting
Location
UAN Pediatric Endocrinology
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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) PHASE3 This is a sub-study of Study RM-493-040 (NCT05774756).
The goal of this su...
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University of Alabama
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Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a) PHASE2 The investigators plan to test the efficacy and safey of 6-months of open-l...
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Enrolling By Invitation
Location
Massachusetts General Hospital
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Setmelanotide in a Single Patient With Partial Lipodystrophy PHASE2 The objective of this single patient study is to assess the safety and effi...
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University of Michigan
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A Study of Setmelanotide in Patients With Prader-Willi Syndrome PHASE2 This is a Phase 2, open-label study designed to assess the safety and effic...
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Active Not Recruiting
Location
University of Florida
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Open-Label Extension Study of Setmelanotide PHASE3 This is an open-label extension study designed to evaluate the long-term sa...
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HonorHealth Research Institute
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Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity PHASE3 To demonstrate statistically significant and clinically meaningful effects ...
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Markham Stouffville Hospital
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