Found 23 matching trials
A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission PHASE4 This study will establish whether prolonged chronic dosing with secukinumab...
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Active Not Recruiting
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Novartis Investigative Site
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Study of the Efficacy and Safety of Secukinumab in Participants With Active Psoriatic Arthritis With Axial Skeleton Involvement PHASE3 The purpose of this study is to demonstrate the efficacy and safety of secu...
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Novartis Investigative Site
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Efficacy at 24 Weeks and Safety, Tolerability and Long Term Efficacy of Secukinumab (AIN457) in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Anti-Tumor Necrosis Factor α (Anti-TNFα) Agents (CAIN457F2309 and CAIN457F2309E1) PHASE3 The core and extension studies assessed the safety and efficacy of secukinu...
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Novartis Investigative Site
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Efficacy and Safety of Subcutaneous Secukinumab for Moderate to Severe Chronic Plaque-type Psoriasis for up to 1 Year PHASE3 This study will assess the safety and efficacy of secukinumab compared to p...
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Novartis Investigative Site
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Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis PHASE3 The study will assess the safety and efficacy of intravenous (10mg/kg) and ...
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Novartis Investigative Site
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Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate PHASE2 The study compared the efficacy and assessed the safety of secukinumab give...
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Novartis Investigative Site
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An Efficacy Study of Secukinumab In Enthesitis of Psoriatic Arthritis Patients PHASE1 Given the role of IL-17 in the development of entheseal-driven pathology, a...
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Chinese Academy of Medical Sciences & Peking Union Medical College
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Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis PHASE3 This study will assess the safety and efficacy of AIN457 as adjunctive ther...
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Novartis Investigative Site
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Efficacy at 24 Weeks and Safety, Tolerability and Long Term Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Rheumatoid Arthritis and an Inadequate Response to Anti-TNFα Agents PHASE3 The core and extension studies assessed the safety and efficacy of secukinu...
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Novartis Investigative Site
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Extension in AS: Sustainability of Benefits, Safety and Tolerability PHASE3 This 3-year extension study aims at making available the treatment with sec...
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Novartis Investigative Site
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