Found 73 matching trials
Dose Ranging Study to Evaluate the Efficacy and Safety of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis PHASE2 Primary objective:
\- to evaluate the efficacy of Sarilumab in participant...
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Investigational Site Number 840006
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Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment PHASE4 A potential application of therapeutic drug monitoring is to predict effica...
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Sint Maartenskliniek
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A Multiple-dose Study of the Safety and Tolerability of REGN88(SAR153191) in Rheumatoid Arthritis Subjects PHASE1 This is a randomized study of the safety and tolerability of multiple doses...
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Multiple Locations
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Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic Mastocytosis PHASE2 Background:
Mast cells help the body fight disease and heal wounds. People...
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National Institutes of Health Clinical Center
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Study on the Use of Sarilumab in Patients With COVID-19 Infection EARLY_PHASE1 Sarilumab is an anti-interleukin-6 human monoclonal antibody, such as tocil...
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Divisione Clinicizzata di Malattie Infettive, ASST FBF-Sacco
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Efficacy of Subcutaneous Sarilumab in Hospitalised Patients With Moderate-severe COVID-19 Infection (SARCOVID) PHASE2 The global health emergency created by the rapid spread of the SARS-CoV-2 c...
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Hospital Universitario de la Princesa
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An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) PHASE2 Primary Objective:
To describe the pharmacokinetic (PK) profile of sarilum...
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Children's Hospital Los Angeles Site Number : 8400416
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Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica PHASE4 This is a randomized, double-blind, placebo-controlled, parallel-group, Pha...
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Denver Arthritis Clinic - Lowry- Site Number : 8400001
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) N/A The study investigators are interested in learning more about how drugs, th...
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Phoenix Children's Hospital
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Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis PHASE1 Primary Objective:
To describe the safety and tolerability, including labo...
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Investigational Site Number 392001
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