Found 0 matching trials
Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet
PHASE3The primary objective of this trial is to evaluate the ability of Phenoptin...
Location
Multiple Locations
A Phase 3, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With PKU Who Have Elevated Phenylalanine Levels
PHASE3The primary objective of this trial is to evaluate the safety and tolerabil...
Location
Multiple Locations
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
PHASE2The investigators will investigate the effect of blood phenylalanine on Kuv...
Location
Department of Biochemistry & Molecular Biology
Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKU
PHASE3This multicenter, open label study is designed to evaluate the safety of Ku...
Location
Multiple Locations
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
NAMore patients with chronic obstructive pulmonary disease (COPD) die from ca...
Location
Augusta University
The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)
N/AThe objective of the study is to determine whether Kuvan™ (sapropterin) imp...
Location
University of Missouri
Evaluation of BH4 Responsiveness in Our PKU Patients
PHASE1This study aims to evaluate BH4 responsiveness in our PKU patients and to c...
Status
Active Not Recruiting
Location
Sohag Faculty of Medicine
Nutritional Status in Phenylketonuria
N/AIn the era of Phenylketonuria (PKU) newborn screening, early diagnosis in t...
Location
Centro Hospitalar Universitário do Porto
The Effectiveness of Kuvan in Amish PKU Patients
PHASE4The purpose of this study is to determine if Amish patients with PKU show r...
Location
University Hospitals Cleveland Medical Center
Neuroimaging and Neurocognitive Assessment and Response to Sapropterin Dihydrochloride Treatment in Phenylketonuria
NAThe investigators will use different types of brain imaging (MRI) in patien...
Location
Children's Research Institute