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A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours
NADespite some encouraging data, systemic treatment of CNS metastases from so...
Location
Institut Jules Bordet
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
PHASE2This phase II trial studies how well de-escalating the drugs dabrafenib and...
Location
University of Alabama at Birmingham
A Phase I/II Study of Azacitidine, Docetaxel, and Prednisone for Metastatic Prostate Cancer Patients
PHASE1Azacitidine can reverse clinical resistance to docetaxel through upregulati...
Location
University of Miami Sylvester Comprehensive Cancer Center
Genetic and Molecular Characterization of Nervous System Lesions
N/APrimary and secondary brain tumors, the leading cause of death from cancer ...
Location
Service de Neurochirurgie - Hôpital de la Pitié Salpêtrière
FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia
PHASE1This phase I trial tests the safety, side effects, and best dose of FH-FOLR...
Location
Fred Hutch/University of Washington/Seattle Children's Cancer Consortium
Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis
N/AThe aim of this research is to understand how lipids such as cholesterol af...
Location
University College London Hospitals NHS Foundation Trust
Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the Lung
PHASE1This phase II trial tests the safety, best dose, and effectiveness of inhal...
Location
Mayo Clinic in Rochester
Immunoregulatory T Lymphocytes Subtypes and Haematopoietic Stem Cell Transplantation (HSCT)
N/AThe purpose of this study is to confirm that invariant NKT lymphocytes (iNK...
Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
N/AGliomas are the most frequent type of primary brain tumors in adults; among...
Location
IRCCS San Raffaele Scientific Institute
Autoimmune Neurological Diseases and Those Secondary to Immunotherapy: Study of Immunological Mechanisms and Research Into Targets of Immune Attack
NAThe pathophysiology of neurological toxicities secondary to immune checkpoi...
Location
Hôpital Bicêtre AP-HP