Found 14 matching trials
A Study to Evaluate the Safety and Tolerability of SX-682 in Combination With Nivolumab as a Maintenance Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma PHASE1 The main purpose of this research study is to determine the maximum tolerab...
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Location
University of Rochester
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Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer PHASE2 The goal of this clinical trial is to study the combination of SX-682 plus ...
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University of California, Los Angeles
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Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer PHASE1 ASpiRE will investigate the effect of the drug SX-682 in combination with A...
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Oncology Institute of Southern Switzerland
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COMPASS Study for Metastatic Castration-resistant Prostate Cancer N/A This study is a companion to the SYNERGY-201 clinical trial (NCT06228053), ...
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UCSF Helen Diller Family Comprehensive Cancer Center
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SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab PHASE1 Cancers attract myeloid-derived suppressor cells (MDSCs) that prevent our o...
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Location
University of Miami
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Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer PHASE1 Background:
Head and neck cancers (HNCs) account for about 5% of all cance...
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National Institutes of Health Clinical Center
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Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT) PHASE1 Background:
Combination immunotherapy techniques are being explored to imp...
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National Institutes of Health Clinical Center
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A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer PHASE2 The purpose of this study is to evaluate the safety and clinical activity o...
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Active Not Recruiting
Location
Johns Hopkins SKCCC
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Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome PHASE1 This study will determine the safety profile, maximum tolerated dose (MTD),...
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SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer PHASE2 This phase II trial tests how well SX-682 and atezolizumab works for the tr...
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Fred Hutch/University of Washington Cancer Consortium
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