Found 9 matching trials
A Mass Balance and Biotransformation Study of [14C]SKLB1028 in Chinese Healthy Male Subjects
PHASE1This is a single-centre, open-label, mass balance and biotransformation stu...
Location
Shanghai Xuhui Central Hospital
A Study of SKLB1028 in Patients With Advanced Solid Tumor
PHASE1The purpose of this study is to evaluate the safety, tolerability, pharmaco...
Location
Henan Cancer Hospital
A Dose Escalation and Food Effect Study of SKLB1028 in Healthy Subjects
PHASE1The purpose of this study was to explore the safety, tolerability and pharm...
Location
Beijing Friendship Hospital, Capital Medical University
A Study of SKLB1028 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia
PHASE1Patients will receive oral SKLB1028 for 28 days to study the side effects, ...
Location
West China Hospital,Sichuan University
SKLB1028, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
PHASE1The purpose of this study is to describe the dose limiting toxicities (DLT)...
Location
West China Hospital of Sichuan University
A Study to Investigate the Drug-drug Interactions (DDIs) of SKLB1028 With Itraconazole, Gemfibrozil or Rifampicin in Healthy Subjects
PHASE1This is a three-part, single-center, open-label phase I clinical study to c...
Location
Beijing Friendship Hospital, Capital Medical University
A Study to Investigate the Drug-drug Interactions (DDIs) Between SKLB1028 and Midazolam in Healthy Subjects
PHASE1This is a single-center, open-label phase I clinical study to investigate t...
Location
Beijing Friendship Hospital, Capital Medical University
A Clinical Study of SKLB1028 Capsule in the Treatment of Recurrence/Refractory AML Patients
PHASE2Patients will receive oral SKLB1028 for 28 days as a course of treatment, a...
Location
West China Hospital,Sichuan University
A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated
PHASE3This is a randomized,multicenter, open-label Phase III, clinical study to c...
Location
West China hospital of Sichuan University