Found 24 matching trials
TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma
PHASE1This phase Ib/II trial studies the side effects and best dose of toll-like ...
Location
Stanford University, School of Medicine
Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab
PHASE1The goal of this Phase 1b clinical trial is to evaluate the safety and effi...
Status
Active Not Recruiting
Location
University of California, San Diego
Safety, Pharmacokinetics, and Pharmacodynamics of SD-101 in Healthy Normal Males
PHASE1The main purpose of this study is to assess the safety, tolerability, and b...
Location
Healthcare Discoveries, Inc.
A Phase I/II Study of Intratumoral Injection of SD-101
PHASE1This phase 1-2 trial studies the side effects and best dose of ipilimumab i...
Location
Stanford University Hospitals and Clinics
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
PHASE2The purpose of this study is to further advance the ability to practice per...
Location
University of Alabama at Birmingham
Safety Study of SD-101 (a Novel C Type Toll-like Receptor 9 (TLR9) Agonist) for the Treatment of Chronic Hepatitis C Virus (HCV) Infection
PHASE1To determine safety, tolerability, and preliminary efficacy of escalating d...
Location
Klinika Chorób Zakaźnych i Hepatologii Collegium Medicum Uniwersytet Mikołaja Kopernika
Study of SD-101 in Combination With Localized Low-dose Radiation in Patients With Untreated Low-grade B-cell Lymphoma
PHASE1To assess the safety and tolerability of escalating doses of SD-101 in comb...
Location
Stanford University School of Medicine
Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma
PHASE1This study is an open-label, phase 1/1b study of the pressure-enabled intra...
Status
Active Not Recruiting
Location
MD Anderson Cancer Center
Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT
PHASE2This is a non-comparative open-label multicenter Phase 2 clinical trial com...
Location
University of California San Francisco
UCDCC#271: Phase I/II Trial of Epacadostat, Intralesional SD101, Radiotherapy in Patients With Lymphoma
PHASE1Checkpoint blockade immunotherapy has revolutionized the management of a va...
Location
University of California Davis Comprehensive Cancer Center