Found 10 matching trials
Evaluation of SAR408701 in Japanese Patients With Advanced Malignant Solid Tumors PHASE1 Primary Objective:
* To evaluate tolerability and safety of SAR408701 when...
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Investigational Site Number : 3920002
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INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701 PHASE2 This study is a prospective, open-label, multi-cohort, exploratory phase II...
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Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC PHASE2 Primary Objective:
* Safety run-in part: to assess the tolerability and to...
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KU Medical Center_Investigational Site Number :8400002
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SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small-cell Lung Cancer Patients PHASE3 Primary Objectives:
* Study was designed with multiple primary endpoints a...
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Florida Cancer Specialists South Division- Site Number : 8400020
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Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab or Ramucirumab and Pembrolizumab in Pretreated Patients With NSQ NSCLC (CARMEN-LC04) PHASE2 Primary Objectives:
Doublet Cohort
Part 1 (safety run-in):
To assess the...
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Henry Ford Hospital Site Number : 8400005
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Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors PHASE1 This is a Phase1, single-arm study for treatment. This is a prospective mul...
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Mary Crowley Cancer Research Center Site Number : 8400002
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Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab in Pretreated Participants With Gastric Cancer PHASE2 Primary Objectives:
Part 1: to confirm the recommended tusamitamab ravtans...
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Investigational Site Number : 0560002
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Evaluation of SAR408701 in Patients With Advanced Solid Tumors PHASE1 Primary Objectives:
* To determine the maximum tolerated dose (MTD) of SAR...
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Yale University School of Medicine Site Number : 840002
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Tusamitamab Ravtansine in NSQ NSCLC Participants With Negative or Moderate CEACAM5 Expression Tumors and High Circulating CEA PHASE2 This is an open label single group, Phase 2, 1-arm study for treatment to e...
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Roswell Park Cancer Institute Site Number : 8400004
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Tusamitamab Ravtansine Monotherapy and in Combination in Patients With CEACAM5-positive Advanced Solid Tumors PHASE2 Primary Objective:
* For Cohort A, Cohort B, and Cohort C Part 2: To asses...
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AdventHealth Orlando Site Number : 8400001
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