Found 19 matching trials
Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function PHASE1 To Assess the Effect of Severe Hepatic or Renal Impairment on the Pharmacok...
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Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir PHASE1 Drug-drug interaction study of Ruzasvir and Bemnifosbuvir...
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Efficacy and Safety of Uprifosbuvir (MK-3682) + Ruzasvir (MK-8408) in Treating Hepatitis C Virus Infection Genotypes 1-6 (MK-3682-041) PHASE2 This is a nonrandomized, multi-site, open-label trial to evaluate a novel t...
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Efficacy and Safety of Uprifosbuvir (MK-3682) With Ruzasvir (MK-8408) in Adults With Chronic Hepatitis C Genotype 1, 2, 3, 4, 5 or 6 Infection (MK-3682-035) PHASE2 This study is an open-label, multi-center trial to evaluate the novel 2-dru...
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Efficacy and Safety of Grazoprevir (+) Uprifosbuvir (+) Ruzasvir (MK-3682B) (MK-5172 + MK-3682 + MK-8408) Fixed Dose Combination in Chronic HCV Participants Failing Prior Antiviral Treatment (MK-3682-021) PHASE2 This is a randomized, multicenter, 2-part, open-label trial of the combinat...
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Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir PHASE1 This study will assess comparative bioavailability and effect of food on a ...
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A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV PHASE2 This is an open-label trial to evaluate safety and efficacy of treatment wi...
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Pharmacokinetics of MK-3682B in Participants With Moderate to Severe Renal Insufficiency (MK-3682B-030) PHASE1 The purpose of this study is to compare the plasma pharmacokinetics (PK) of...
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Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Digoxin and Rosuvastatin PHASE1 Drug-drug interaction study between Bemnifosbuvir/Ruzasvir and Digoxin or R...
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A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029) PHASE1 This is a non-randomized, open-label, single-dose study to evaluate the pha...
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