Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)
PHASE1
The purpose of this study is to test any good or bad effects of the study d...
Status
Completed
Location
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL
PHASE2
The goal of this clinical trial is to evaluate the efficacy and safety of a...
Status
Recruiting
Location
The First Affiliated Hospital of Fujian Medical University
Selinexor, High-dose Methotrexate, and Rituximab Combined With Radiotherapy for Newly Diagnosed, Transplant-ineligible Patients With Central Nervous System Lymphoma: An Open-label, Single-arm, Multicenter Phase II Study
PHASE2
This phase II clinical trial is designed to evaluate a novel combination tr...
Status
Recruiting
Location
The Second Affiliated Hospital of Soochow University