A Pharmacokinetic Study of Narlaprevir as a Single Dose or With Ritonavir Combination in Patients With Hepatic Impairment and Healthy Matched Volunteers
PHASE1
This study was conducted to evaluate narlaprevir (NVR) pharmacokinetics (PK...
A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ABT-450 With Ritonavir (ABT-450/r) Dosed in Combination With ABT-072 and Ribavirin (RBV)
PHASE2
The purpose of this study is to evaluate the safety, tolerability, pharmaco...
TMC114-TiDP3-C176 - A Study in Healthy Volunteers Investigating the Bioequivalence Between Two Commercially Available 400-mg Tablets to One New 800-mg Tablet of Darunavir (DRV) in the Presence of Low-dose Ritonavir Under Fed and Fasted Conditions
PHASE1
In this study participants will be given 800 mg darunavir, either as one 80...
Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected Adults
PHASE4
Despite the clinical significance of potential interactions between antimal...
Status
Completed
Location
Groote Schuur Hospital, Ward J51, Old Main Building