Found 17 matching trials
A Phase II Trial of Ridaforolimus and Exemestane, Compared to Ridaforolimus, Dalotuzumab and Exemestane in Participants With Breast Cancer (MK-8669-064) PHASE2 The purpose of the study is to evaluate the efficacy of the triplet of rida...
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Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009) PHASE2 This clinical trial will study the use of ridaforolimus in metastatic breas...
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Extension Trial of Deforolimus (Ridaforolimus, MK-8669) in Participants With Advanced Cancer (MK-8669-038) PHASE2 To describe the long-term safety of deforolimus (ridaforolimus, MK-8669) in...
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Study of Oral Ridaforolimus (AP23573, MK-8669) to Treat Patients With Refractory or Advanced Malignancies (MK-8669-016 AM4)(COMPLETED) PHASE1 The primary objective of this current phase I trial is to study the safety ...
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Effect of Ridaforolimus on the Pharmacokinetics of Midazolam (Study MK-8669-044) PHASE1 The purpose of this study is to compare the pharmacokinetic profile of mida...
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Phase II Study of Ridaforolimus (MK-8669) With Metastatic Bone or Soft-tissue Sarcoma Patients (MK-8669-030 AM1) PHASE2 The study evaluates efficacy of Ridaforolimus when administered as maintena...
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Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049) PHASE1 This is a two part study of the drug MK-8669 (ridaforolimus) given with MK-...
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Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (MK-8669-007 AM6) PHASE2 The purpose of this study is to compare progression-free survival (PFS) of ...
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Ridaforolimus in Treatment of Sarcoma-SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Ridaforolimus)(8669-011 AM6) PHASE3 The purpose of this study is to determine whether maintenance therapy with ...
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Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED) PHASE1 The purpose of this study is to assess the safety, tolerability, and recomm...
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