Found 13 matching trials
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC PHASE1 The purpose of this platform study is to evaluate the safety, tolerability,...
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Banner MD Anderson Cancer Center
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Expanded Access Program for Daraxonrasib (RMC-6236) in Previously Treated Metastatic Pancreatic Adenocarcinoma N/A This Expanded Access Program (EAP) is intended to provide daraxonrasib to e...
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Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) PHASE3 The purpose of this study is to evaluate the safety and efficacy of a novel...
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Active Not Recruiting
Location
Banner MD Anderson Cancer Center
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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors PHASE1 The purpose of this platform study is to evaluate the safety, tolerability,...
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Ironwood Cancer and Research Centers
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Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301) PHASE3 The purpose of this study is to evaluate the safety and efficacy of a novel...
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Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors PHASE1 This study is to evaluate the safety, tolerability, and PK profiles of Elir...
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A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5) PHASE2 This is an open-label, multicenter Phase 2 study evaluating BMS-986504 in p...
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Local Institution - 0096
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Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS PHASE1 Evaluate the safety and tolerability of RMC-6236 in adults with specific RA...
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UC Irvine/Chao Family Comprehensive Cancer Center
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A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103) PHASE1 The study aims to determine maximum tolerated dose (MTD) or recommended com...
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Active Not Recruiting
Location
Comprehensive Blood and Cancer Center
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Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients PHASE1 TNG462-C102 is a Phase 1/2, open-label, multicenter study designed to deter...
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Mayo Clinic Scottsdale
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