Found 32 matching trials
Dose Ranging Study to Evaluate the Efficacy and Safety of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis PHASE2 Primary objective:
\- to evaluate the efficacy of Sarilumab in participant...
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Investigational Site Number 840006
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A Multiple-dose Study of the Safety and Tolerability of REGN88(SAR153191) in Rheumatoid Arthritis Subjects PHASE1 This is a randomized study of the safety and tolerability of multiple doses...
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Multiple Locations
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An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA) PHASE2 Primary Objective:
To describe the pharmacokinetic (PK) profile of sarilum...
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Children's Hospital Los Angeles Site Number : 8400416
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Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis PHASE1 Primary Objective:
To describe the safety and tolerability, including labo...
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Investigational Site Number 392001
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To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN) PHASE3 Primary Objective:
To assess, in the same study, the safety of sarilumab a...
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Investigational Site Number 840152
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To Evaluate the Immunogenicity and Safety of Sarilumab Administered as Monotherapy in Patients With Rheumatoid Arthritis (RA) PHASE3 Primary Objective:
To evaluate the immunogenicity of sarilumab administere...
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Investigational Site Number 840072
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Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis PHASE2 Primary Objective:
To evaluate the efficacy of sarilumab at Week 16 in par...
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Investigational Site Number 840008
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Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients PHASE2 Primary Objectives:
Part A (dose ranging study):
To demonstrate that sari...
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Investigational Site Number 840070
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A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS) PHASE2 Primary Objective:
To describe the pharmacokinetic (PK) profile of sarilum...
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Investigational Site Number : 0320004
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Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica PHASE3 Primary Objective:
To evaluate the efficacy of KEVZARA (sarilumab) in part...
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Investigational Site Number 8400003
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