Found 71 matching trials
A Study of RC48-ADC Combined with JS001 for Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma PHASE2 This study will evaluate the efficacy and safety of intravenous RC48-ADC co...
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Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
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ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0) PHASE2 This is an open-label, single-arm, Phase II investigator-initiated trial of...
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The First Bethune Hospital of Jilin University
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Neoadjuvant RC48 Plus Gemcitabine in HER2-Expressing MIBC PHASE3 Objectives: To evaluate the non-inferiority of disitamab vedotin plus gemci...
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The First Affiliated Hospital of Anhui Medical University
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Disitamab Vedotin Combined With Ivonescimab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer PHASE1 This is a single-arm, open-label, Phase Ib/II clinical trial designed to ev...
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Sun Yat-sen University Cancer Center
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DV in Combination With Pertuzumab With or Without Toripalimab Neoadjuvant Therapy With HER2-positive Breast Cancer PHASE2 The purpose of this study is to evaluate the efficacy and safety of Disitam...
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Fudan University Shanghai Cancer Center
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RC48-ADC Combined With S-1 for First-line Treatment of Advanced Gastroesophageal Adenocarcinoma With Moderate Expression of HER2 PHASE1 This study was a single-arm, open, multi-center Phase Ib/II clinical trial ...
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Beijing Friendship Hospital
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A Study of RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer PHASE1 This is an open-label, single-arm, Phase Ib/II investigator-initiated trial...
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Beijing Cancer Hospital
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A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2 PHASE2 This study is being done to see if a drug called disitamab vedotin, alone o...
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Banner Gateway Medical Center
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A Study of RC48-ADC Combined With Cadonilimab(AK104)in the Treatment of HER2-expression Locally Advanced or Metastatic Urothelial Carcinoma PHASE2 This study will evaluate the efficacy and safety of RC48-ADC combined with ...
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Cancer Institute and Hospital, Chinese Academy of Medical Sciences
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A Clinical Study of the Efficacy and Safety of Disitamab Vedotin in Combination With Radiotherapy for the Adjuvant Treatment of HER2 Overexpressing UTUC Patients With High Risk Factors for Recurrence After Radical Surgery PHASE2 In this study, 60 patients with HER2 overexpression UTUC with high-risk rec...
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Peking University First Hospital
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