Found 16 matching trials
Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric Patient PHASE4 The purpose of this study is to evaluate whether a therapy that uses a mach...
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Multiple Locations
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Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Exploratory Efficacy Parameters of AIR DNase™in Patients With Cystic Fibrosis Previously Treated With Pulmozyme® PHASE2 This study evaluates the Safety,Tolerability, Pharmacokinetics and Explorat...
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A Comparative Safety and Pharmacokinetic Study of JHL1922 and Pulmozyme® in Healthy Subjects PHASE1 This is a double-blind, randomised, 2 single-doses and then repeated-dose (...
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JHL Biotech Investigational Site
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Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients NA Despite the lack of trials proving the efficacy of DNase in non cystic fibr...
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Presbyterian Hospital
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RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum PHASE4 Serine proteases belonging to the elastase family are mainly responsible fo...
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University Hospital - Tours
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A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis PHASE4 This was a Phase IV, multicenter, randomized, double-blind, placebo-control...
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Multiple Locations
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A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis PHASE4 This phase IV, multicenter, randomized, open-label, two-period crossover st...
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Multiple Locations
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Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma PHASE3 Severe hypoxemia following trauma may happen in many circumstances (aspirat...
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University Hospital, Strasbourg, france
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VATS Surgery Compared to Drainage in the Treatment of Pleural Empyema NA Pleura empyema is a frequent disease with a high morbidity and a mortality ...
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Aarhus University Hospital
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Usefulness of DORNASE in COVID-19 on HFNO PHASE4 COVID-19 pneumonia manifests among others with a thick bronhial secretion. ...
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University Medical Centre Ljubljana
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