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Reversibility of Apixaban Anticoagulation With the Four Factor Prothrombin Complex Concentrate Kcentra PHASE1 Apixaban is an anticoagulant (also known as blood thinner) approved by the ...
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Thomas Jefferson University Hosptial
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The ZEro PLASma Trial (ZEPLAST): Avoidance of Fresh Frozen Plasma in Cardiac Surgery PHASE3 Prospective, randomized, double blind trial. The rationale of the study is ...
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IRCCS Policlinico San Donato
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A Study to Assess the Independent Effects of 4-Factor Prothrombin Complex Concentrate and Tranexamic Acid on Bleeding/Pharmacodynamics in Healthy Participants PHASE1 The purpose of this study is to assess the independent effects of both a 4-...
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Multiple Locations
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Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study ) PHASE3 This is a prospective, multicenter, randomized, double-blind, placebo-contr...
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Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects PHASE3 The purpose of this study is to evaluate efficacy and safety of a Prothromb...
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Nippon Medical School Hospital
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Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. PHASE3 Patients who undergo percutaneous coronary intervention (PCI) are commonly ...
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Istituto Cardiocentro Ticino
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PCC Treatment for Hemophilia Patients With Inhibitor(2022PCC-A) PHASE4 This study is a multicenter, prospective, single-arm exploratory clinical t...
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Institute of haematology and Blood diseases hospital
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A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of JNJ-64179375 in Healthy Male Subjects PHASE1 The purpose of this study is to assess the safety and tolerability of JNJ-6...
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Multiple Locations
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SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis PHASE3 The purpose of the aPCC-emicizumab safety study is to investigate the hemos...
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Children's Healthcare of Atlanta
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A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers PHASE1 The purpose of this study is to assess the use of 2 different Prothrombin C...
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Multiple Locations
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