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Study of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE or RIXUBIS N/A This 6-month prospective outcomes study addresses the association between t...
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Orthopaedic Hospital DBA Orthopaedic Hemophilia Treatment Center
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Study of Ataluren (PTC124) in Hemophilia A and B PHASE2 Hemophilia A (HA) and hemophilia B (HB) are inherited bleeding disorders ca...
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The Bleeding and Clotting Disorders Institute
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REPlaCE- Randomized Trial Evaluating the Use of Prothrombin Complex concEntrate to Improve Survival in Patients With Traumatic Coagulopathy PHASE2 Uncontrolled hemorrhage continues to be a significant source of mortality f...
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Multiple Locations
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Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors PHASE3 Study B7841007 is an open-label extension study to assess the long-term saf...
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University of Iowa
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A Study to Evaluate the Safety and Efficacy of VGB-R04 in Adult Hemophilia B Patients PHASE1 A multicenter, open, non-randomized, phase I/II, two-phase clinical study. ...
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Shanghai Vitalgen Biopharma Co.,Ltd.
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Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation PHASE3 This study is comparing the use of Kcentra vs. standard transfusion in pati...
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University of Maryland
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FEIBA to Optimize Postcardiopulmonary Bypass Hemostasis in Pediatric Cardiac Patients PHASE2 The purpose of this research is to understand if the medication called FEIB...
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Multiple Locations
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Dose-Response in PD and Safety of Cofact Under VKA Anticoagulation PHASE1 This is a randomized, open label, placebo-controlled, parallel design, sing...
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PRA Health Sciences
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Fixed-dose Activated Versus Variable-dose Inactivated Prothrombin Complex Concentrate for Warfarin-associated Major Bleed N/A This study aims to assess a fixed-dose regimen of activated prothrombin com...
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Multiple Locations
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Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk. PHASE3 To demonstrate that the efficacy of OCTAPLEX as a reversal agent in patient...
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Octapharma Research Site
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