Found 117 matching trials
Long Term Safety Study of PRALUENT PHASE4 The primary objective of the study was to evaluate the long term safety of ...
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Regeneron Research Site
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PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung PHASE2 PCSK9 mediates immune checkpoint blockade resistance by downregulating tumo...
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Active Not Recruiting
Location
Moffitt Cancer Center
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Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study) PHASE3 Atherosclerosis in the setting of HIV infection is distinct and includes in...
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San Francisco General Hospital
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Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy PHASE3 Primary Objective:
To collect real-use (usability) data assessing the robu...
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Investigational Site Number 8400024
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A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia PHASE2 This study is researching an experimental drug called alirocumab, referred ...
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Pinnacle Research Group
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Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis PHASE3 Calcific aortic stenosis (CAS) can cause severe adverse cardiac events, but...
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Beijing Anzhen Hospital, Capital Medical University
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Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy Drinkers PHASE1 Background:
Drinking alcohol can lead to swelling and injury in the liver....
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National Institutes of Health Clinical Center
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Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia PHASE3 Primary Objective:
To demonstrate the reduction of low-density lipoprotein...
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Investigational Site Number 1560027
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Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia PHASE2 The primary objective of the study is to evaluate the reduction of LDL-C by...
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Cedars-Sinai Medical Center
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An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia PHASE2 Primary Objective:
To evaluate the effect of alirocumab on low-density lip...
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Investigational Site Number 8400002
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