A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
PHASE3
The purpose of this study is to evaluate the efficacy and safety of divaras...
A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanoma
PHASE1
This is an open-label, multicenter, Phase Ib, dose-escalation and cohort-ex...
A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors
PHASE1
GSK2118436 is an orally administered, potent and selective small molecule B...
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate
PHASE1
RATIONALE: Drugs used in chemotherapy, such as 17-N-allylamino-17-demethoxy...
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
PHASE3
In this study, the efficacy and safety of two nilotinib doses, 300 mg twice...
Status
Completed
Location
University of California at Los Angeles Dept. of Hematology Clinic