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Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706 PHASE1 The clinical schedule will consist of 3 injections of CD40.HIVRI.Env (VRIPR...
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In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors PHASE1 This phase I trial evaluates the safety and effectiveness of in situ immuno...
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Location
Los Angeles General Medical Center
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A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma PHASE1 This is a study to determine the clinical benefit (how well the drug works)...
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California Pacific Medical Center Research Institute
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Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs PHASE1 The main purpose of this study is to determine the safety of using the comb...
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Pediatric Hematology/Oncology University of Louisville
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Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy PHASE1 This is a phase 1 open-label study to evaluate the safety and immunogenicit...
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Washington University School of Medicine
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A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM PHASE1 This research study is studying a targeted therapy as a possible treatment ...
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Location
Massachusetts General Hospital
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Study to Evaluate the Safety and Immunogenicity of Poly ICLC (Hiltonol) in Healthy Volunteers PHASE1 Vaccines induce protective immunity against numerous infectious diseases. H...
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The Rockefeller University
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Safety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted Vaccine PHASE1 In this study, Genocea is evaluating an investigational, personalized adjuv...
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UC San Diego Moores Cancer Center
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Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma PHASE1 This phase I trial studies the side effects and how well of pembrolizumab a...
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Active Not Recruiting
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Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLC PHASE1 Veterans with advanced lung cancer may benefit from recent advances in tech...
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Michael E. DeBakey VA Medical Center, Houston, TX
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