Found 107 matching trials
Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer PHASE1 This phase I clinical trial evaluates the safety and feasibility of adminis...
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UCLA / Jonsson Comprehensive Cancer Center
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Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma PHASE1 This phase I trial studies the side effects and best dose of genetically mo...
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Active Not Recruiting
Location
City of Hope Medical Center
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O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas PHASE1 This phase I/II trial studies the side effects and best dose of temozolomid...
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Fred Hutch/University of Washington Cancer Consortium
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Reduced Intensity Transplantation for Severe Sickle Cell Disease PHASE2 This study is being done to test a transplant method that may have fewer si...
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St. Jude Children's Research Hospital
Treatments Being Tested
hydroxyurea, azathioprine, alemtuzumab, thioptepa, low dose total body irradiation and sirolimus hydroxyurea, azathioprine, alemtuzumab, thiotepa, plerixafor, low dose total body irradiation, cyclophosphamide and sirolimus Learn More & Join Trial
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia PHASE1 Background:
Sickle cell disease (SCD) is an inherited disorder of the bloo...
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Active Not Recruiting
Location
National Institutes of Health Clinical Center
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Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L PHASE2 The purpose of this study is to compare the effects, good and bad, of two w...
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Memoral Sloan Kettering Cancer Center
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Study of Plerixafor for Rescue of Poor Mobilizers in Autologous Stem Cell Transplant PHASE2 Plerixafor, administered at a dose of 240 ug/kg, potentiates the effect of ...
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Duke University Medical Center
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Scleroderma Treatment With Autologous Transplant (STAT) Study PHASE2 This phase II trial studies how well giving cyclophosphamide and anti-thymo...
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City of Hope Comprehensive Cancer Center
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Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy PHASE1 Background:
X-linked severe combined immunodeficiency (XSCID) is a rare in...
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Enrolling By Invitation
Location
National Institutes of Health Clinical Center
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Clinical And Economic Impact Of Upfront Plerixafor In Autologous Transplantation PHASE2 This protocol will investigate the effectiveness of plerixafor in the up-fr...
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Shands Cancer Hospital at the University of Florida
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