Found 32 matching trials
Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection NA Malaria, a disease caused by the parasite Plasmodium, is one of the world's...
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Radboud university medical center
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Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) PHASE1 This study intends to test the hypothesis that the malaria antigen PfPEBS, ...
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Centre Hospitalier Universitaire Vaudois (CHUV)
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Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults PHASE1 The proposed study is a Phase 1 study with controlled human malaria infecti...
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Clinical Trials Center, WRAIR
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Malaria Challenge in Healthy Volunteers PHASE1 The purpose of this study is to determine if sterile, protective immunity t...
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Seattle Biomedical Research Institute's Malaria Clinical Trials Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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Safety and Causal Prophylactic Efficacy of KAF156 in a Controlled Human Malaria Challenge Model PHASE1 This study is designed to investigate the safety and causal prophylactic ef...
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Novartis Investigative Site
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Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 NA This is a single-center, open label study. The primary aim of this project ...
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Radboud university medical center
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Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali PHASE1 Background:
Malaria is still a health problem in Sub-Saharan Africa. Death...
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University of Bamako (USTTB/MRTC)
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Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea PHASE1 This is a phase 1, randomized regimen optimization study of PfSPZ Vaccine i...
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Baney Clinical Research Center
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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