Found 12 matching trials
Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER) PHASE2 The primary purpose of this study is to assess the tolerability, pharmacoki...
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National Cancer Center Hospital
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Neoadjuvant Pimicotinib Combined With Surgery Versus Upfront Surgery for Diffuse Tenosynovial Giant Cell Tumor PHASE2 Tenosynovial giant cell tumor (TGCT) is a rare neoplasm predominantly occur...
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Department of Orthopedics, The Second Affiliated Hospital, Zhejiang University School of Medicine
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Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER) PHASE3 The goal of this clinical trial is to assess the efficacy and safety of Pim...
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Active Not Recruiting
Location
Precision NextGen Oncology
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A Study to Investigate The Effect of Pimicotinib on The Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin In Healthy Subjects PHASE1 This is a an open-label, fixed-sequence DDI study conducted in Chinese heal...
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The First Affiliated Hospital Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
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A Phase II Study Evaluating the Efficacy and Safety of ABSK021 (Pimicotinib)) in the Treatment of cGvHD Chronic Graft Versus Host Disease (cGvHD) PHASE2 This is a multicenter, single arm, open label phase II clinical study in Ch...
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Enrolling By Invitation
Location
Peking University People's Hospital
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A Study to Evaluate the Effect of a High-fat Meal on the Exposure of Pimicotinib Capsule in Healthy Subjects PHASE1 This is a study to evaluate the impact of a high - fat meal on the exposure...
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Active Not Recruiting
Location
The First Hospital of Jilin University
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A Mass Balance Study of [14C]ABSK021 PHASE1 This study is a single-site, open-label, single-cohort, single-dose study t...
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The First Affiliated Hospital of SOOCHOW UNIVERSITY
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A Study to Evaluate the Relative Bioavailability of Pimicotinib Capsules Containing Free Base in Different Proportions in Healthy Subjects PHASE1 This is an open-label, randomized, two-treatment, single-dose, two-way cros...
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The First Hospital of Jilin University
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A Study to Evaluate the the Bioequivalence of Two Different Pimicotinib Capsules in Healthy Subjects PHASE1 This is a study to evaluate bioequivalence and tolerability of two differen...
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The First Hospital of Jilin University
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The Study to Assess the Pharmacokinetics of Pimicotinib in Subjects With Mild and Moderate Hepatic Impairment Relative to Subjects With Normal Hepatic Function PHASE1 This is a phase 1, open-label, parallel-group, single-center study to evalu...
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The first hospital of Jilin University
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